M8-B (hydrochloride) |
| Catalog No.GC18296 |
M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin , or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 883976-12-3
Sample solution is provided at 25 µL, 10mM.
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M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin , or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively). It displays no effect at other TRP channels. M8-B decreases deep body temperature in wild-type mice and rats but has no effect on body temperature in TRPM8 KO mice.
Review for M8-B (hydrochloride)
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
Review for M8-B (hydrochloride)
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