Nitrocefin (Synonyms: Nitrocephin) |
| Catalog No.GC14823 |
니트로세핀은 β-락탐 고리의 아미드 결합이 β-락타마제에 의해 가수분해됨에 따라 노란색에서 빨간색으로 독특한 색상 변화를 겪는 발색 β-락타마제 기질입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 41906-86-9
Sample solution is provided at 25 µL, 10mM.
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Nitrocefin is a chromogenic cephalosporin substrate which is used for detection of β-lactamases. β-lactamases are enzymes produced by various microbes that mediate resistance to β-lactam antibiotics such as penicillins and cephamycins. Comparing to other methods for β-lactamases detection, nitrocefin is more sensitive while using few materials and inexpensive equipment. The color change by nitrocefin can be followed quantitatively by measuring changes in absorption between 380 to 500 nm region[1].
Reference:
[1] O'Callaghan, Cynthia H et al. Novel Method for Detection of B-Lactamases by Using a Chromogenic Cephalosporin Substrate. Antimicrobial Agents and Chemotherapy. 1972 Apr; 1(4):283-288.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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