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Squarunkin A hydrochloride

Catalog No.GC50430

Squarunkin A 염산염은 강력하고 선택적인 UNC119-화물 상호작용 억제제(UNC119A-미리스토일화된 Src N-말단 펩티드 상호작용을 억제하기 위한 10nM의 IC50)입니다. Squarunkin A 염산염은 세포에서 Src 키나제의 활성화를 방해합니다.

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Squarunkin A hydrochloride Chemical Structure

Cas No.: 2253744-55-5

Size 가격 재고 수량
10 mg
US$234.00
재고 있음
50 mg
US$988.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Potent inhibitor of UNC119 chaperone protein-cargo interaction (IC50 = 10 nM for inhibition of UNC119A - myristoylated Src N-terminal peptide interaction). Disrupts activation of Src kinase in vitro.

Mejuch et al (2017) Small-molecule inhibition of the UNC119-cargo interaction. Angew.Chem.Int.Ed. 56 6181 PMID:28471079

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 4 reference(s) in Google Scholar.)

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