DNA Damage/DNA Repair

Hygromycin A is a spirochete-active antibiotic that inhibits protein synthesis by binding the 70S ribosomal peptidyl transferase center.

A thymosin β4-derived peptide

A fluorescently labeled form of dCTP

An internal standard for the quantification of mycophenolic acid

A carbamate pesticide

An internal standard for the quantification of uracil

An azaarene

Tumulosic Acid, a triterpenoid, inhibits KLK5 protease activity (IC50= 14.84 μM).

A fecal pigment and metabolite of bilirubin

Clindamycin (hydrochloride hydrate) is a lincosamide antibiotic used to treat severe infections caused by susceptible anaerobes , streptococci , staphylococci , and pneumococci . Clindamycin primary clinical applications include osteomyelitis, respiratory tract infections, biliary tract infections, endocarditis, otitis media, skin and soft tissue infections, and sepsis.

An active metabolite of cytarabine

An inducer of immunogenic cancer cell death

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

Potent Chk2 inhibitor

Topoisomerase I inhibitor

JTE 607 dihydrochloride, a highly selective inflammatory cytokine synthesis inhibitor, protects from endotoxin shock in mice.

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2; also enhances CRISPR-Cpf1-mediated genome editing

BRACO 19 trihydrochloride is a potent telomerase/telomere inhibitor with an IC 50 value of 115±18nM, which prevents telomerase capping and catalysis.

Selective cdk7 inhibitor

Potent and selective LIMK inhibitor; antitumor

Inhibitor of Clk and DYRK kinases

6-Hydroxy-DL-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DL-DOPA can be used for the research of cancer.

AMG 18 hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.