BS 181 dihydrochloride |
| Catalog No.GC50217 |
Selective cdk7 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1883548-83-1
Sample solution is provided at 25 µL, 10mM.
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Selective cdk7 inhibitor (IC50 = 21 nM). Displays >40-fold selectivity for cdk7 over others cdks. Promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro and inhibits MCF-7 tumor xenograft growth in mice.
Ali et al (2009) The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity. Cancer Res. 69 6208 PMID:19638587
Average Rating: 5 (Based on Reviews and 16 reference(s) in Google Scholar.)
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