DNA Damage/DNA Repair
Research Areas
- MTH1(4)
- PARP(103)
- ATM/ATR(31)
- DNA Alkylating(23)
- DNA Ligases(3)
- DNA Methyltransferase(27)
- DNA-PK(28)
- HDAC(143)
- Nucleoside Antimetabolite/Analogue(194)
- Telomerase(15)
- Topoisomerase(193)
- tankyrase(5)
- Antifolate(33)
- CDK(299)
- Checkpoint Kinase (Chk)(36)
- CRISPR/Cas9(9)
- Deubiquitinase(84)
- DNA Alkylator/Crosslinker(87)
- DNA/RNA Synthesis(575)
- Eukaryotic Initiation Factor (eIF)(33)
- IRE1(25)
- LIM Kinase (LIMK)(12)
- TOPK(6)
- Casein Kinase(59)
- DNA Intercalating Agents(8)
- DNA/RNA Oxidative Damage(13)
- Poly(ADP-ribose) Glycohydrolase (PARG)(5)
- Early 2 Factor (E2F)(2)
- Zinc Finger Protein(1)
Products Related to DNA Damage/DNA Repair(1968)
- GC79068Telomeric G4s ligand 2CAS: 3094716-52-3Purity: >98%
Telomeric G4s ligand 2 is an orally active, selective ligand of telomeric G-quadruplex (G4), with an IC 50 of 0.4 μM.
- GC79070WWQ-03-012CAS: 3076807-15-0Purity: >98.00%
WWQ-03-012 is a selective DESI2 inhibitor with an IC 50 of 47.3 nM.
- GC79076Chktide acetatePurity: >99.00%
Chktide acetate is a synthetic peptide substrate applicable for activity assays of Chk1 kinase and cyk/CaMKII.
- GC79078trans-AzoTABCAS: 1109241-72-6Purity: >96.00%
trans-AzoTAB is a photoresponsive potassium/sodium/calcium channel modulator and DNA-binding agent.
- GC790792-FormylaminobenzaldehydeCAS: 25559-38-0Purity: >98%
2-Formylaminobenzaldehyde (2-Formylphenylformamide) is a nucleoside metabolite.
- GC790805-Acetamidopentanoic acidCAS: 1072-10-2Purity: >98.50%
5-Acetamidopentanoic acid (5-(Acetylamino)-pentanoic acid) is a fungal metabolite [1] .
- GC790814,6-DihydroxyquinolineCAS: 3517-61-1Purity: >98.00%
4,6-Dihydroxyquinoline is an oxidation product of 5-hydroxykynuramine [1] .
- GC79082N-Hydroxyl-tryptamineCAS: 4761-34-6Purity: >99.00%
N-Hydroxyl-tryptamine is a product formed from tryptamine catalyzed by flavin monooxygenase (FMO) [1] .
- GC790832’-ThiouridineCAS: 31281-28-4Purity: >98.00%
2'-Thiouridine is a key modified nucleoside at the wobble position of tRNA anticodons.
- GC790844-Hydroxyphenylacetylglutamic acidCAS: 1029120-37-3Purity: >99.50%
4-Hydroxyphenylacetylglutamic acid is a metabolite of Morus alba L [1] .
- GC790852′-O-Methyl-5-hydromethylcytidineCAS: 2088197-31-1Purity: >98%
2′-O-Methyl-5-hydromethylcytidine (hm5Cm) is a 5-hydroxymethylcytidine derivative.
- GC790869,10-Dihydroxy-12,13-epoxyoctadecanoateCAS: 127105-40-2Purity: >98%
9,10-Dihydroxy-12,13-epoxyoctadecanoate is a metabolite that is involved in the linoleic acid metabolism pathway [1] .
- GC790872'-Deoxy-N-methyl-AMP ammoniumPurity: >98.00%
2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor.
- GC79088Allochenodeoxycholic acidCAS: 15357-34-3Purity: >99.50%
Allochenodeoxycholic acid is a nucleoside metabolite.
- GC790892-Methylthio-cis-zeatin ribosideCAS: 52049-48-6Purity: >98%
2-Methylthio-cis-zeatin riboside (ms2io6A), a hypermodified adenosine derivative, is present in the transfer RNA of Salmonella ryphimurium.
- GC790903α,7α-DihydroxycoprostaneCAS: 3862-26-8Purity: >99.50%
3α,7α-Dihydroxycoprostane is a metabolite of cholest-4-en-3-one-7α-ol [1] .
- GC79091dUDP disodiumCAS: 102814-06-2Purity: >95.00%
dUDP disodium is a nucleotide that plays a crucial role in the synthesis of DNA.
- GC790923'-O-TBDMS-2'-dG(iBu)CAS: 99540-94-0Purity: >98%
3'-O-TBDMS-2'-dG(iBu) is a monomeric raw material that can be used for nucleic acid synthesis.
- GC790932'-O-POM-rA(Bz)CAS: 2842847-62-3Purity: >99.00%
2'-O-POM-rA(Bz) is a monomeric raw material that can be used for nucleic acid synthesis.
- GC790942',3'-Di-O-iBu-rG(iBu)CAS: 56489-75-9Purity: >98.00%
2',3'-Di-O-iBu-rG(iBu) is a monomeric raw material that can be used for nucleic acid synthesis.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC79068 | Telomeric G4s ligand 2 | 3094716-52-3 | >98% | |
Telomeric G4s ligand 2 is an orally active, selective ligand of telomeric G-quadruplex (G4), with an IC 50 of 0.4 μM. | ||||
| GC79069 | IA107 | - | >98.00% | |
IA107 is a potent, selective, and allosteric IRE1α RNase ( IC 50 = 16 nM (non phosphorylated), IC 50 = 9 nM (phosphorylated)) inhibitor. | ||||
| GC79070 | WWQ-03-012 | 3076807-15-0 | >98.00% | |
WWQ-03-012 is a selective DESI2 inhibitor with an IC 50 of 47.3 nM. | ||||
| GC79072 | MS6076 | - | >98% | |
MS6076 is a mitochondrial protease ClpP agonist. | ||||
| GC79075 | NVS1.1 | - | >98% | |
NVS1.1 is an orally active, blood-brain barrier-penetrant eRF1 degrader. | ||||
| GC79076 | Chktide acetate | - | >99.00% | |
Chktide acetate is a synthetic peptide substrate applicable for activity assays of Chk1 kinase and cyk/CaMKII. | ||||
| GC79077 | DDO-6600 | 2640292-37-9 | >98.00% | |
DDO-6600 is a covalent Hsp90 inhibitor. | ||||
| GC79078 | trans-AzoTAB | 1109241-72-6 | >96.00% | |
trans-AzoTAB is a photoresponsive potassium/sodium/calcium channel modulator and DNA-binding agent. | ||||
| GC79079 | 2-Formylaminobenzaldehyde | 25559-38-0 | >98% | |
2-Formylaminobenzaldehyde (2-Formylphenylformamide) is a nucleoside metabolite. | ||||
| GC79080 | 5-Acetamidopentanoic acid | 1072-10-2 | >98.50% | |
5-Acetamidopentanoic acid (5-(Acetylamino)-pentanoic acid) is a fungal metabolite [1] . | ||||
| GC79081 | 4,6-Dihydroxyquinoline | 3517-61-1 | >98.00% | |
4,6-Dihydroxyquinoline is an oxidation product of 5-hydroxykynuramine [1] . | ||||
| GC79082 | N-Hydroxyl-tryptamine | 4761-34-6 | >99.00% | |
N-Hydroxyl-tryptamine is a product formed from tryptamine catalyzed by flavin monooxygenase (FMO) [1] . | ||||
| GC79083 | 2’-Thiouridine | 31281-28-4 | >98.00% | |
2'-Thiouridine is a key modified nucleoside at the wobble position of tRNA anticodons. | ||||
| GC79084 | 4-Hydroxyphenylacetylglutamic acid | 1029120-37-3 | >99.50% | |
4-Hydroxyphenylacetylglutamic acid is a metabolite of Morus alba L [1] . | ||||
| GC79085 | 2′-O-Methyl-5-hydromethylcytidine | 2088197-31-1 | >98% | |
2′-O-Methyl-5-hydromethylcytidine (hm5Cm) is a 5-hydroxymethylcytidine derivative. | ||||
| GC79086 | 9,10-Dihydroxy-12,13-epoxyoctadecanoate | 127105-40-2 | >98% | |
9,10-Dihydroxy-12,13-epoxyoctadecanoate is a metabolite that is involved in the linoleic acid metabolism pathway [1] . | ||||
| GC79087 | 2'-Deoxy-N-methyl-AMP ammonium | - | >98.00% | |
2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor. | ||||
| GC79088 | Allochenodeoxycholic acid | 15357-34-3 | >99.50% | |
Allochenodeoxycholic acid is a nucleoside metabolite. | ||||
| GC79089 | 2-Methylthio-cis-zeatin riboside | 52049-48-6 | >98% | |
2-Methylthio-cis-zeatin riboside (ms2io6A), a hypermodified adenosine derivative, is present in the transfer RNA of Salmonella ryphimurium. | ||||
| GC79090 | 3α,7α-Dihydroxycoprostane | 3862-26-8 | >99.50% | |
3α,7α-Dihydroxycoprostane is a metabolite of cholest-4-en-3-one-7α-ol [1] . | ||||
| GC79091 | dUDP disodium | 102814-06-2 | >95.00% | |
dUDP disodium is a nucleotide that plays a crucial role in the synthesis of DNA. | ||||
| GC79092 | 3'-O-TBDMS-2'-dG(iBu) | 99540-94-0 | >98% | |
3'-O-TBDMS-2'-dG(iBu) is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC79093 | 2'-O-POM-rA(Bz) | 2842847-62-3 | >99.00% | |
2'-O-POM-rA(Bz) is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC79094 | 2',3'-Di-O-iBu-rG(iBu) | 56489-75-9 | >98.00% | |
2',3'-Di-O-iBu-rG(iBu) is a monomeric raw material that can be used for nucleic acid synthesis. | ||||