Metabolism

Terbuthylazine -d 9 is the deuterium labeled Terbuthylazine.

cis-V-11-0711 is the cis form of V-11-0711.

is a cyclic nucleotide phosphodiesterase-4B ( PDE4B ) inhibitor.

DIM-3,5-Cl2 is an inverse NR4A1/NR4A2 agonist with K D values of 7.7 μM and 12.0 μM for NR4A1 and NR4A2, respectively.

GW 590735 (Standard) is the analytical standard of GW 590735.

TRPV1 antagonist 10 is an orally active and potent TRPV1 antagonist ( IC 50 = 33.06 nM), moderate to weak URAT1 ( IC 50 = 22.51 μM) and GLUT9 (60.25% at 50 μM) inhibitor.

HDAC11-IN-5 is a selective, potent and orally active HDAC11 inhibitor with an IC 50 of 0.021 μM.

5-Hydroxytryptophol-O-glucuronide (UGT1A6) is an authentic glucuronide standard and probe metabolite.

H-D-Val-Leu-Lys-AFC TFA (Plasmin substrate TFA) is a plasmin -specific fluorescent substrate.

Idescarpin is a phenolic glycoside compound isolated from Idesia polycarpa and exhibits an extremely bitter taste.

NOTA-DPI-4452 TFA is a trifluoroacetate derivative with DPI-4452 as the parent peptide.

UBA6-IN-1 hydrochloride is a UBA6/UBE1L2 inhibitor ( IC 50 ≤50 nM) that acts by reducing the level of squalene epoxidase ( SQLE ).

RB 101 hydrochloride is a blood-brain barrier-crossing prodrug as well as aminopeptidase N and neutral endopeptidase-24.11 inhibitor.

CP61 acetate is a CtBP1 and CtBP2 inhibitor that binds to dimeric CtBP1 and allosterically inhibits NADH binding, disrupting the NADH -dependent dimerization of CtBP1 and CtBP2, inducing aberrant mitosis and micronucleus formation, thereby inhibiting cell proliferation and colony formation.

A Certified Reference Material

An internal standard for the quantification of ethyl-β-D-glucuronide

A synthetic intermediate of anastrozole

An aggregation-induced emission fluorogen

A metabolite of cortisol

A cell-permeable stearated peptide

A perfluoroalkyl substance

A perfluoroalkyl substance

A peptide ADGRG2 agonist

A disaccharide microbial metabolite with diverse biological activities