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Acetaminophen sulfate (potassium salt) (Synonyms: 4-Acetamidophenol sulfate, APAP sulfate, 4'-Hydroxyacetanilide sulfate, Paracetamol sulfate)

Katalog-Nr.GC42694 Copy One-Click Copy Product Info

Acetaminophen sulfate is a metabolite of acetaminophen.

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Acetaminophen sulfate (potassium salt) Chemische Struktur

Cas No.: 32113-41-0

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Sample solution is provided at 25 µL, 10mM.



Description of Acetaminophen sulfate (potassium salt)

Acetaminophen sulfate is a metabolite of acetaminophen . Acetaminophen is an analgesic and antipyretic that undergoes sulfonation by sulfotransferases in humans, rats, and mice to form acetaminophen sulfate, which is excreted in urine. Acetaminophen inhibits COX-2 activity by more than 80%, albeit at relatively high doses, while it is less effective against COX-1. Acetaminophen is enzymatically and non-enzymatically converted to several reactive metabolites that contribute to adverse or indirect effects, including liver injury. Acetaminophen is reportedly used as cutting agent in heroin.

Chemical Properties of Acetaminophen sulfate (potassium salt)

Cas No. 32113-41-0 SDF
Überlieferungen 4-Acetamidophenol sulfate, APAP sulfate, 4'-Hydroxyacetanilide sulfate, Paracetamol sulfate
Canonical SMILES CC(NC1=CC=C(OS([O-])(=O)=O)C=C1)=O.[K+]
Formula C8H8NO5S•K M.Wt 269.3
Löslichkeit Water: Soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Acetaminophen sulfate (potassium salt)

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1 mg 5 mg 10 mg
1 mM 3.7133 mL 18.5667 mL 37.1333 mL
5 mM 742.7 μL 3.7133 mL 7.4267 mL
10 mM 371.3 μL 1.8567 mL 3.7133 mL
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In vivo Formulation Calculator (Clear solution) of Acetaminophen sulfate (potassium salt)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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