Alternariol monomethyl ether (Synonyms: AME, NSC 638262) |
| Katalog-Nr.GC18437 |
Alternariolmonomethylether, isoliert aus den Wurzeln von Anthocleista djalonensis (Loganiaceae), ist ein wichtiger taxonomischer Marker der Pflanzenart.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 23452-05-3
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Alternariol monomethyl ether (AME) is a mycotoxin originally isolated from A. brassicae extracts. AME is a common contaminant in cereal grains such as wheat, barley, and sorghum that is cytotoxic to bacterial (MIC = 500 μg/disc for B. mycoides in a bacterial halo assay) and mammalian cells (IC50 = 120 μM in HCT116 cells). It inhibits human topoisomerase II and bacterial gyrase at initial inhibitory concentrations of 25 and 10 μM, respectively. AME selectively inhibits monoamine oxidase A (MOA-A; Ki = 0.34 μM). AME also provokes DNA damage that induces mitochondrial permeability transition pore-mediated activation of apoptosis.
Review for Alternariol monomethyl ether
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
Review for Alternariol monomethyl ether
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *