AMG 333 |
| Katalog-Nr.GC65611 |
AMG 333 ist ein potenter und hochselektiver TRPM8-Antagonist mit einem IC50 von 13 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1416799-28-4
Sample solution is provided at 25 µL, 10mM.
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AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM.
[1]. Horne DB, et al. Discovery of TRPM8 Antagonist ( S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine. J Med Chem. 2018 Sep 27;61(18):8186-8201.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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