Angoline |
| Katalog-Nr.GC60585 |
Angolin ist ein potenter und selektiver Inhibitor des IL6/STAT3-Signalwegs mit einem IC50-Wert von 11,56 μM. Angolin hemmt die STAT3-Phosphorylierung und die Expression seines Zielgens und hemmt die Proliferation von Krebszellen.
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Cas No.: 21080-31-9
Sample solution is provided at 25 µL, 10mM.
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Angoline is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].
[1]. Jiawei Liu, et al. Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum. Phytomedicine. Jul-Aug 2014;21(8-9):1088-91.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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