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AR-13324 analog mesylate

Katalog-Nr.GC34300

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AR-13324 analog mesylate Chemische Struktur

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10mM (in 1mL DMSO)
447,00 $
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2mg
214,00 $
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5mg
321,00 $
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10mg
459,00 $
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50mg
1.379,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

AR-13324 analog mesylate is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.

[1]. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4. [2]. Levy B, et al. Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am J Ophthalmol. 2015 May;159(5):980-5.e1.

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