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BMS-1001

Katalog-Nr.GC25160

BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes.

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BMS-1001 Chemische Struktur

Cas No.: 2113650-03-4

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5mg
189,00 $
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25mg
572,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes.

BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is effective in attenuating the inhibitory effect of the cell surface-associated PD-L1.[1]

[1] Lukasz Skalniak, et al. Oncotarget. 2017 Aug 7;8(42):72167-72181.

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