N-[(4-Aminophenyl)methyl]adenosine |
| Katalog-Nr.GC36676 |
N-[(4-Aminophenyl)methyl]adenosin ist ein Adenosinrezeptor-Inhibitor mit einem Ki von 29 nM fÜr Ratten-Ecto-5'-Nucleotidase.
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![N-[(4-Aminophenyl)methyl]adenosine Chemische Struktur](/media/struct/GC3/GC36676.png "N-[(4-Aminophenyl)methyl]adenosine Chemische Struktur")
Cas No.: 95523-13-0
Sample solution is provided at 25 µL, 10mM.
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N-[(4-Aminophenyl)methyl]adenosine is a adenosine receptor inhibitor, with Ki of 29 nM for Rat ecto-5′-Nucleotidase.IC50 value: 29.0 ± 1.7 nM (Ki) Target: Adenosine Receptor
[1]. Bhattarai S, et al. α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58(15):6248-63. [2]. Chen JB, et al. Design and synthesis of novel dual-action compounds targeting the adenosine A(2A) receptor and adenosine transporter for neuroprotection. ChemMedChem. 2011 Aug 1;6(8):1390-400. [3]. Zhu Z, et al. Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. Bioorg Med Chem. 2008 Apr 1;16(7):3848-65.
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