Prostaglandin D2-d4 (Synonyms: PGD2d4)

Name: Prostaglandin D2-d4
Brand: GlpBio
SKU: GC47988
Availability: InStock
Rating: 5 (9 reviews)

Katalog-Nr.GC47988

An internal standard for the quantification of prostaglandin D₂

Products are for research use only. Not for human use. We do not sell to patients.

Prostaglandin D2-d4 Chemische Struktur

Cas No.: 211105-29-2

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25 μg	128,00 $	Auf Lager
50 μg	245,00 $	Auf Lager
100 μg	462,00 $	Auf Lager

Tel：(909) 407-4943 Email: sales@glpbio.com

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Sample solution is provided at 25 µL, 10mM.

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Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

View current batch:

Purity: >99.00%

Prostaglandin D₂-d₄ (PGD₂-d₄) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGD₂ by GC- or LC-mass spectrometry. PGD₂ is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD₂, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD₂ is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as β-trace.2,3 In the brain, PGD₂ produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD₂ inhibits human ovarian tumor cell proliferation with an IC₅₀ of 6.8 µM.

N/A

Cas No.	211105-29-2	SDF
Überlieferungen	PGD2d4
Canonical SMILES	O[C@@H](C1)[C@H](C/C=C\C([2H])([2H])C([2H])([2H])CC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)C1=O
Formula	C20H28D4O5	M.Wt	356.5
Löslichkeit	DMF: >100 mg/ml (from PGD2),DMSO: >50 mg/ml (from PGD2),Ethanol: >75 mg/ml (from PGD2),PBS pH 7.2: >5 mg/ml (from PGD2)	Storage	Store at -20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	2.805 mL	14.0252 mL	28.0505 mL
	5 mM	0.561 mL	2.805 mL	5.6101 mL
	10 mM	0.2805 mL	1.4025 mL	2.805 mL

Molaritätsrechner
Verdünnung-Rechner

Berechnen

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal:μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for Prostaglandin D2-d4

Average Rating: 5 ★★★★★ (Based on Reviews and 9 reference(s) in Google Scholar.)

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Prostaglandin D2-d4 (Synonyms: PGD2d4)

Kundenbewertungen

GlpBio Citations

Bioactive Compounds Premium Provider

GlpBio Produkte in seriösen Veröffentlichungen zitiert

Product Documents

Quality Control & SDS

Complete Stock Solution Preparation Table

Molaritätsrechner

Verdünnung-Rechner

In vivo Formulation Calculator (Clear solution)

Bewertungen