Prostaglandins
Produkte für Prostaglandins
- Bestell-Nr. Artikelname Informationen
- GC41431 δ12-Prostaglandin D2 Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2.
- GC41476 δ17-6-keto Prostaglandin F1α δ17-6-keto Prostaglandin F1α (δ17-6-keto PGF1α) is a cyclooxygenase (COX) product of eicosapentaenoic acid (EPA) in various tissues such as seminal vesicles, lung, Polymorphonuclear leukocytes, and ocular tissues.
- GC49515 (±)-Ibuprofen-d3 (sodium salt) An internal standard for the quantification of (±)-ibuprofen
- GC41315 (±)-Ketoprofen Glucuronide (±)-Ketoprofen glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen.
- GC45278 (±)-Ketoprofen-d3
- GC41685 (±)-WIN 55,212 (mesylate) (±)-WIN 55,212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki value of 62.3 and 3.3 nM for human recombinant central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively.
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GC40270
(±)5(6)-DiHET
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
- GC40281 (+)-15-epi Cloprostenol Cloprostenol is a synthetic prostaglandin F2α (PGF2α) analog and a potent FP receptor agonist.
- GC40282 (+)-5-trans Cloprostenol Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses.
- GC45260 (+)-Cloprostenol isopropyl ester (+)-Cloprostenolisopropylester, ein Prostaglandin F2α Analoga, ist das Zwischenprodukt von (+)-Cloprostenol.
- GC45262 (+)-Cloprostenol methyl ester (+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α).
- GC40716 (R)-Butaprost Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype.
- GC41714 (R)-Butaprost (free acid) Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype.
- GC49179 (S)-O-Desmethyl Naproxen A metabolite of (S)-naproxen
- GC41761 1-(6-Methoxy-2-naphthyl)ethanol 1-(6-Methoxy-2-naphthyl)ethanol is a potential impurity in commercial preparations of naproxen.
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GC18235
1-O-Hexadecyl-sn-glycerol
1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether.
- GC49366 1-Salicylate Glucuronide A metabolite of salicylic acid and aspirin
- GC40577 11β-13,14-dihydro-15-keto Prostaglandin F2α 11β-13,14-dihydro-15-keto Prostaglandin F2α (11β-13,14-dihydro-15-keto PGF2α) is a metabolite of Prostaglandin D2 (PGD2) in the 15-hydroxy PGDH pathway.
- GC41243 11β-Misoprostol Misoprostol is a widely sold analog of prostaglandin E1 (PGE1) which has potent but relatively non-selective agonist activity with respect to the prostanoid EP receptor subgroup.
- GC41410 11β-Prostaglandin E2 11β-Prostaglandin E2 (11β-Dinoproston), ein Prostanoid-Derivat, hemmt die [3H]PGE2-Bindung an Hypothalamusmembranen bei der Ratte mit einem Ki von 53,3 nM.
- GC41432 11β-Prostaglandin F1β 11β-PGF1β is the stereoisomer of PGF1α with both C-9 and C-11 hydroxyls inverted.
- GC41404 11β-Prostaglandin F2α Ethanolamide 11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.
- GC18634 11-deoxy Prostaglandin E1 11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1.
- GC41121 11-deoxy Prostaglandin E2 11-deoxy Prostaglandin E2 (11-deoxy PGE2) is a stable, synthetic analog of PGE2.
- GC41401 11-deoxy Prostaglandin F1α 11-deoxy PGF1α is a synthetic analog of PGF1α.
- GC41402 11-deoxy Prostaglandin F1β 11-deoxy PGF1β is a synthetic analog of PGF1β.
- GC40274 11-deoxy Prostaglandin F2α 11-deoxy PGF2α is a synthetic analog of PGF2α.
- GC40275 11-deoxy Prostaglandin F2β 11-deoxy Prostaglandin F2β (11-deoxy PGF2β) is an analog of PGF2β.
- GC40335 11-deoxy-11-methylene Prostaglandin D2 Prostaglandin D2 is one of the five primary enzymatic prostaglandins derived directly from PGH2.
- GC41879 11-deoxy-11-methylene-15-keto Prostaglandin D2 Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2.
- GC40390 11-deoxy-16,16-dimethyl Prostaglandin E2 11-deoxy-16,16-dimethyl PGE2 is a stable synthetic analog of PGE2.
- GC41880 11-keto Fluprostenol 11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency.
- GC18617 11β-Prostaglandin E1 11β-Prostaglandin E1 (11β-PGE1) is an epimerized form of PGE1 at the C-11 position.
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GC18637
11β-Prostaglandin F2α
11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.
- GC40745 13,14-dehydro-15-cyclohexyl Carbaprostacyclin 13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2.
- GC41433 13,14-dihydro Prostaglandin E1 13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound.
- GC41902 13,14-dihydro Prostaglandin F1α 13,14-dihydro PGF1α is a potential metabolite of PGF1α.
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GC41434
13,14-dihydro Prostaglandin F2α
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain.
- GC41435 13,14-dihydro-15(R)-Prostaglandin E1 13,14-dihydro-15(R)-Prostaglandin E1 (13,14-dihydro-15(R)-PGE1) is an analog of 13,14-dihydro-PGE1 , which has the hydroxyl group at C-15 in the unnatural R configuration.
- GC41097 13,14-dihydro-15-keto Prostaglandin A2 PGE2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2, which is present in the plasma of humans and other mammals.
- GC40578 13,14-dihydro-15-keto Prostaglandin D1 Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product.
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GC41411
13,14-dihydro-15-keto Prostaglandin D2
13,14-dihydro-15-keto Prostaglandin D2 (13,14-dihydro-15-keto PGD2) is a metabolite of PGD2 which is formed through the 15-hydroxy PGDH pathway.
- GC18783 13,14-dihydro-15-keto Prostaglandin E1 13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity.
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GC41413
13,14-dihydro-15-keto Prostaglandin E2
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is the primary metabolite of PGE2 in plasma.
- GC41436 13,14-dihydro-15-keto Prostaglandin F1α 13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach.
- GC40579 13,14-dihydro-15-keto Prostaglandin F2α 13,14-dihydro-15-keto Prostaglandin F2α (13,14-dihydro-15-keto PGF2α) is the first prominent plasma metabolite of PGF2α in the 15-hydroxy PGDH pathway.
- GC40625 13,14-dihydro-15-keto-tetranor Prostaglandin D2 A common metabolic pathway for several prostaglandins (PGs), including PGD2, involves the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs.
- GC40626 13,14-dihydro-15-keto-tetranor Prostaglandin E2 A common metabolic pathway for several prostaglandins (PG), including PGE2, involves the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs.
- GC41903 13,14-dihydro-15-keto-tetranor Prostaglandin F1α The metabolism of F series prostaglandins (PGs), including PGF1α and PGF2α, commonly begins with the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs.
- GC41904 13,14-dihydro-15-keto-tetranor Prostaglandin F1β 13,14-dihydro-15-keto tetranor-Prostaglandin F1β is a major urinary metabolite of PGE2 that is excreted in guinea pig urine at a concentration range of 1.34-2.74 μg/kg.
- GC41905 13,14-dihydro-16,16-difluoro Prostaglandin E1 Prostaglandin E1 (PGE1) is produced by the metabolism of dihomo-γ-linolenic acid (DGLA) by the cyclooxygenase pathway.
- GC41472 15(R),19(R)-hydroxy Prostaglandin E2 19(R)-Hydroxylated prostaglandins occur in μg/ml concentrations in the semen of certain mammalian species, especially primates.
- GC40532 15(R),19(R)-hydroxy Prostaglandin F2α 19(R)-Hydroxylated prostaglandins (PGs) occur in μg/ml concentrations in the semen of certain mammalian species, especially primates.
- GC41921 15(R)-15-methyl Prostaglandin A2 Arbaprostil (15(R)-15-methyl prostaglandin E2) is a synthetic prostaglandin E2 (PGE2) analog developed for its cytoprotective activity.
- GC41164 15(R)-15-methyl Prostaglandin D2 15(R)-15-methyl Prostaglandin D2 (15(R)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2.
- GC41165 15(R)-15-methyl Prostaglandin E2 15(R)-15-methyl Prostaglandin E2 (15(R)-15-methyl PGE2) is a prodrug for the potent PGE2 analog 15(S)-15-methyl PGE2.
- GC41440 15(R)-15-methyl Prostaglandin F2α 15(R)-15-methyl PGF2α is a metabolically stable analog of PGF2α.
- GC41244 15(R)-15-methyl Prostaglandin F2α methyl ester 15(R)-15-methyl Prostaglandin F2α methyl ester (15(R)-15-methyl PGF2α methyl ester) is a lipid soluble prodrug form of 15(R)-15-methyl PGF2α with increased membrane permeability.
- GC40988 15(R)-17-phenyl trinor Prostaglandin F2α 17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name 17-phenyl trinor PGF2α ethyl amide.
- GC40648 15(R)-17-phenyl trinor Prostaglandin F2α ethyl amide 15(R)-17-phenyl trinor Prostaglandin F2α ethyl amide (15(R)-17-phenyl trinor PGF2α ethyl amide) is an isomer of bimatoprost, characterized by an inverted (β) hydroxyl group at C-15.
- GC41922 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15.
- GC41416 15(R)-Prostaglandin D2 Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane GPCR, the DP1 receptor.
- GC41417 15(R)-Prostaglandin E2 15(R)-Prostaglandin E2 (15(R)-PGE2) is the C-15 epimer of the naturally occurring 15(S)-PGE2.
- GC46439 15(R)-Prostaglandin F1α The C-15 epimer of PGF1α
- GC40581 15(R)-Prostaglandin F2α 15(R)-PGF2α is the C-15 epimer of the naturally occurring mammalian autacoid PGF2α.
- GC41166 15(S)-15-methyl Prostaglandin D2 15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2.
- GC18767 15(S)-15-methyl Prostaglandin E1 15(S)-15-methyl Prostaglandin E1 (15(S)-15-methyl PGE1) is a metabolically stable synthetic analog of PGE1 .
- GC41167 15(S)-15-methyl Prostaglandin E2 15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2.
- GC41924 15(S)-15-methyl Prostaglandin F2α isopropyl ester 15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor.
- GC18372 15(S)-15-methyl Prostaglandin F2α methyl ester 15(S)-15-methyl PGF2α methyl ester is a derivative of 15(S)-15-methyl PGF2α with increased membrane permeability.
- GC41226 15(S)-acetate Prostaglandin A2 methyl ester 15(S)-acetate Prostaglandin A2 methyl ester is a 15-acetylated derivative of prostaglandin A2 methyl ester.
- GC40283 15(S)-Fluprostenol (+)-15(R)-Fluprostenol isopropyl ester is a prodrug (Travoprost) which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid.
- GC41589 15(S)-Fluprostenol isopropyl ester 15(S)-Fluprostenol isopropyl ester (15(S)-Flu-Ipr) is the unnatural C-15 epimer of Travoprost.
- GC41093 15(S)-Latanoprost 15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost.
- GC49036 15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α A nitric oxide-donating derivative of 17-phenyl trinor prostaglandin F2α
- GC41168 15-cyclohexyl pentanor Prostaglandin F2α 15-cyclohexyl pentanor PGF2α is an analog of PGF2α with resistance to 15-hydroxy PGDH metabolism.
- GC40375 15-deoxy-δ12,14-Prostaglandin A1 15-deoxy-δ12,14-Prostaglandin A1 (15-deoxy-δ12,14-PGA1) is a synthetic PGA1 analog.
- GC40350 15-deoxy-δ12,14-Prostaglandin A2 15-deoxy-δ12,14-PGA2 is a synthetic analog of PGA2.
- GC41928 15-deoxy-δ12,14-Prostaglandin J2 Glutathione 15-deoxy-δ12,14-Prostaglandin J2 Glutathione (15-deoxy-δ12,14-PGJ2 Glutathione) is a non-enzymatic adduct formed from 15-deoxy-δ12,14-PGJ2 and glutathione.
- GC41125 15-epi Prostaglandin A1 15-epi PGA1 is the 15(R) stereoisomer of PGA1.
- GC41931 15-keto Cloprostenol isopropyl ester 15-keto Cloprostenol isopropyl ester is a potential impurity found in commercial cloprostenol isopropyl ester preparations.
- GC41933 15-keto Fluprostenol isopropyl ester 15-Keto-Fluprostenol-Isopropylester (15-Keto-Fluprostenol-Isopropylester) ist ein Metabolit von Travoprost.
- GC41934 15-keto Latanoprost 15-Keto-Latanoprost ist ein Metabolit von Latanoprost, einem augendrucksenkenden Mittel.
- GC40989 15-keto Latanoprost (free acid) 15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals.
- GC41103 15-keto Prostaglandin A1 Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.
- GC18320 15-keto Prostaglandin E1 15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH.
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GC40605
15-keto Prostaglandin E2
15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 formed by 15-hydroxy PGDH.
- GC40582 15-keto Prostaglandin F1α 15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH.
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GC41418
15-keto Prostaglandin F2α
15-keto Prostaglandin F2α (15-keto PGF2α) is the first metabolite of PGF2α.
- GC41936 15-keto-17-phenyl trinor Prostaglandin F2α Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.
- GC41159 16,16-dimethyl Prostaglandin D2 16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2.
- GC18777 16,16-dimethyl Prostaglandin E1 16,16-dimethyl PGE1 is a metabolically stable synthetic analog of PGE1.
- GC41943 16,16-dimethyl Prostaglandin E2 p-(p-acetamidobenzamido) phenyl ester The p-(p-acetamidobenzamido) phenyl ester is a crystalline derivative of 16,16-dimethyl PGE2 and a potential prodrug.
- GC18774 16,16-dimethyl Prostaglandin F2α 16,16-dimethyl PGF2α is a metabolically stable analog of PGF2α.
- GC18803 16,16-dimethyl Prostaglandin F2β 16,16-dimethyl PGF2β is a metabolically stable analog of PGF2β.
- GC40762 16-phenoxy Prostaglandin F2α ethyl amide Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
- GC18785 16-phenoxy tetranor Prostaglandin A2 16-phenoxy tetranor PGA2 is a minor metabolite found in human plasma after intravenous administration of sulprostone.
- GC41447 16-phenoxy tetranor Prostaglandin E2 16-phenoxy tetranor PGE2 is the free acid form of sulprostone formed by the hydrolysis of the methylsulfonamide bond.
- GC41946 16-phenoxy tetranor Prostaglandin F2α 16-phenoxy PGF2α is a metabolically stable analog of PGF2α.
- GC41947 16-phenoxy tetranor Prostaglandin F2α cyclopropyl methyl amide The actions of many clinical F-series prostaglandins (PGs), including those used for estrous synchronization and for reduction of intraocular pressure (IOP), are mediated through the PGF2α (FP) receptor.