Mycophenolate Mofetil (Synonyms: MMF, RS 61443) |
| Katalog-Nr.GC13614 |
A prodrug form of mycophenolic acid
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 128794-94-5
Sample solution is provided at 25 µL, 10mM.
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Mycophenolate Mofetil is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50s of 39 nM and 27 nM, respectively.
References:
[1]. Nakanishi, T., et al., Effect of the inosine 5'-monophosphate dehydrogenase inhibitor BMS-566419 on rat cardiac allograft rejection. Int Immunopharmacol, 2010. 10(1): p. 91-7.
[2]. Dehghani, F., et al., Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil. Neuropathol Appl Neurobiol, 2010. 36(7): p. 598-611.
[3]. Ozgen, M., et al., Mycophenolate mofetil and daclizumab targeting T lymphocytes in bleomycin-induced experimental scleroderma. Clin Exp Dermatol, 2012. 37(1): p. 48-54.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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