CMD178 |
| Katalog-Nr.GC34238 |
CMD178 ist ein Leitpeptid, das die durch IL-2/s IL-2Rα-Signalgebung induzierte Expression von Foxp3 und STAT5 konsequent reduziert und die Entwicklung von Treg-Zellen hemmt.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling. CMD178 also is an inhibitor of STAT5 and inhibit Treg cell development[1].
[1]. Price-Troska T, et al. Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides. Invest New Drugs. 2018 Apr 26.
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
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