CS-2660 (JNJ-38158471) |
| Katalog-Nr.GC25313 |
CS-2660 (JNJ-38158471) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50 of 40 nM. CS-2660 (JNJ-38158471) also inhibits closely related tyrosine kinases such as RET (c-RET) and Kit (c-Kit) with IC50 of 180 nM and 500 nM，while it has no significant activity (>1 microM) against VEGFR-1 and VEGFR-3.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 951151-97-6
Sample solution is provided at 25 µL, 10mM.
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CS-2660 (JNJ-38158471) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50 of 40 nM. CS-2660 (JNJ-38158471) also inhibits closely related tyrosine kinases such as RET (c-RET) and Kit (c-Kit) with IC50 of 180 nM and 500 nM，while it has no significant activity (>1 microM) against VEGFR-1 and VEGFR-3.
[1] Kenneth R LaMontagne, et al. Angiogenesis. 2009;12(3):287-96.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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