DBCO-PEG4-amine |
| Katalog-Nr.GC39605 |
DBCO-PEG4-Amin ist ein PEG-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann. DBCO-PEG4-Amin ist ein spaltbarer ADC-Linker, der bei der Synthese von AntikÖrper-Wirkstoff-Konjugaten (ADCs) verwendet wird. DBCO-PEG4-Amin kann bei der Synthese von FPM-PEG4-DBCO (einem homobifunktionellen Azid-zu-Azid-Vernetzer) verwendet werden.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1840886-10-3
Sample solution is provided at 25 µL, 10mM.
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DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker)[1].
[1]. Florinas S, et al. A Nanoparticle Platform To Evaluate Bioconjugation and Receptor-Mediated Cell Uptake Using Cross-Linked Polyion Complex Micelles Bearing Antibody Fragments. Biomacromolecules. 2016 May 9;17(5):1818-33.
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