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DM3 (Synonyms: Maytansinoid DM3)

Katalog-Nr.GC60143

DM3 (Maytansinoid DM3) ist ein Maytansin-Analogon, das Disulfid- oder Thiolgruppen und einen Tubulin-Inhibitor trÄgt, und ist eine zytotoxische Einheit von AntikÖrper-Wirkstoff-Konjugaten (ADCs).

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DM3 Chemische Struktur

Cas No.: 796073-54-6

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs)[1].

[1]. Chen H, et al. Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy. Molecules. 2017 Aug 1;22(8).

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