DM3 (Synonyms: Maytansinoid DM3) |
| カタログ番号GC60143 |
DM3 (メイタンシノイド DM3) は、ジスルフィド基またはチオール基を有するメイタンシン類似体であり、チューブリン阻害剤であり、抗体薬物複合体 (ADC) の細胞毒性部分です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 796073-54-6
Sample solution is provided at 25 µL, 10mM.
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DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs)[1].
[1]. Chen H, et al. Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy. Molecules. 2017 Aug 1;22(8).
Review for DM3
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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