Emedastine |
| Katalog-Nr.GC39378 |
Emedastin ist ein oral aktiver, selektiver und hochaffiner Histamin-H1-Rezeptorantagonist mit einem Ki-Wert von 1,3 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 87233-61-2
Sample solution is provided at 25 µL, 10mM.
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Emedastine is an orally active, selective and high affinity histamine H1-receptor antagonist with a Ki value of 1.3 nM. Emedastine is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis[1][2][3].
[1]. Sharif NA, et al. Emedastine: a potent, high affinity histamine H1-receptor-selective antagonist for ocular use: receptor binding and second messenger studies. J Ocul Pharmacol. 1994 Winter;10(4):653-64. [2]. Murota H, et al. Emedastine difumarate: a review of its potential ameliorating effect for tissue remodeling in allergic diseases. Expert Opin Pharmacother. 2009 Aug;10(11):1859-67. [3]. Andoh T, et al. Involvement of blockade of leukotriene B(4) action in anti-pruritic effects of emedastine in mice. Eur J Pharmacol. 2000 Oct 6;406(1):149-52.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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