EX-527 R-enantiomer (Synonyms: (R)-EX-527) |
| Katalog-Nr.GC17126 |
EX-527 R-Enantiomer ((R)-EX-527) ist ein R-Enantiomer von Selisistat. Selisistat (EX-527) ist ein potenter und selektiver SIRT1-Inhibitor mit einem IC50-Wert von 98 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 848193-69-1
Sample solution is provided at 25 µL, 10mM.
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Selisistat R-enantiomer (EX-527 R-enantiomer) is much less active R-enantiomer of Selisistat, with an IC50 of > 100 μM for SIRT1.
References:
[1]. Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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