EZM0414 |
Katalog-Nr.GC64900 |
EZM0414 ist ein potenter, selektiver, oral bioverfÜgbarer Inhibitor von SETD2 (IC50 = 18 nM im biochemischen SETD2-Assay; IC50 = 34 nM im zellulÄren Assay). EZM0414 kann fÜr die Erforschung des rezidivierten oder refraktÄren multiplen Myeloms und des diffusen großzelligen B-Zell-Lymphoms verwendet werden.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2411748-50-8
Sample solution is provided at 25 µL, 10mM.
EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 (IC50=18 nM in SETD2 biochemical assay; IC50=34 nM in cellular assay). EZM0414 can be used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma[1].
[1]. Jennifer Totman, et al. Pharmacologic Inhibition of the Histone Methyltransferase SETD2 with EZM0414 As a Novel Therapeutic Strategy in Relapsed or Refractory Multiple Myeloma and Diffuse Large B-cell Lymphoma.
Average Rating: 5
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