Apigenin-7-glucuronide |
| Katalog-Nr.GC35369 |
Apigenin-7-Glucuronid konnte die AktivitÄten von Matrix-Metalloproteinasen (MMP) mit IC50-Werten von 12,87, 22,39, 17,52, 0,27 μM fÜr MMP-3, MMP-8, MMP-9 bzw. MMP-13 hemmen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 29741-09-1
Sample solution is provided at 25 µL, 10mM.
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Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively. MMP-3|12.87 μM (IC50)|MMP-8|22.39 μM (IC50)|MMP-9|17.52 μM (IC50)|MMP13|0.27 μM (IC50)
Apigenin-7-Oglucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively [1]. Scutellarin A also inhibits the migrated capacity of ACHN and 786-O cells in a dose-dependent manner. It is also revealed that after treatment with Scutellarin A (30, 60, and 90 μM) for 24 h, the apoptosis rates in ACHN and 786-O cells are remarkably enhanced dose-dependently when compared to the control groups[2].
[1]. CrascÌ L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911. [2]. Deng W, et al. Scutellarin inhibits human renal cancer cell proliferation and migration via upregulation of PTEN. Biomed Pharmacother. 2018 Nov;107:1505-1513.
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