BAY-678 racemate |
| Katalog-Nr.GC35476 |
BAY-678-Racemat ist ein Racemat von BAY-678.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 675103-35-2
Sample solution is provided at 25 µL, 10mM.
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BAY-678 racemate is a racemate of BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
[1]. von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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