Galanin Receptor Ligand M35 |
| Katalog-Nr.GC36102 |
Der Galanin-Rezeptor-Ligand M35 ist ein hochaffiner Ligand und Antagonist des Galanin-Rezeptors (Kd = 0,1 nM).
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Cas No.: 142846-71-7
Sample solution is provided at 25 µL, 10mM.
Galanin Receptor Ligand M35 is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. Galanin Receptor Ligand M35 exerts a Ki values of 0.11 and 2.0 nM for human GalR1 and GalR2, respectively[1][2]. Ki: 0.11 nM (GalR1), 2.0 nM (GalR2)[2]
[1]. Kask K, et al. Binding and agonist/antagonist actions of M35, galanin(1-13)-bradykinin(2-9)amide chimeric peptide, in Rin m 5F insulinoma cells. Regul Pept. 1995 Nov 10;59(3):341-8. [2]. Webling KE, et al. Galanin receptors and ligands. Front Endocrinol (Lausanne). 2012 Dec 7;3:146.
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