Gomisin J |
| Katalog-Nr.GC36178 |
Gomisin J ist ein Lignan mit geringem Molekulargewicht, das in Schisandra chinensis vorkommt und dessen vasodilatatorische AktivitÄt nachgewiesen wurde.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 66280-25-9
Sample solution is provided at 25 µL, 10mM.
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Gomisin J is a small molecular weight lignan found in Schisandra chinensis and has been demonstrated to have vasodilatory activity[1]. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+/calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells. gomisin J has potential benefits in treating nonalcoholic fatty liver disease[2]. AMPK Ca2+
[1]. Ye BH, et al. Preventive effect of gomisin J from Schisandra chinensis on angiotensin II-induced hypertension via an increased nitric oxide bioavailability. Hypertens Res. 2015 Mar;38(3):169-77. [2]. Kim M, et al. Gomisin J Inhibits Oleic Acid-Induced Hepatic Lipogenesis by Activation of the AMPK-Dependent Pathway and Inhibition of the Hepatokine Fetuin-A in HepG2 Cells. J Agric Food Chem. 2015 Nov 11;63(44):9729-39.
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