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HIV-1 integrase inhibitor 3

Katalog-Nr.GC36234

HIV-1-Integrase-Inhibitor 3 ist ein HIV-1-Integrase-Strangtransfer(INST)-Inhibitor mit einem IC50 von 2,7 nM.

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HIV-1 integrase inhibitor 3 Chemische Struktur

Cas No.: 1638504-56-9

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. IC50: 2.7 nM (INST)[1]

HIV-1 integrase inhibitor 3 (compound 4c) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. HIV-1 integrase inhibitor 3 also displays an antiviral inhibitory potency against the Q148H/G140S mutant with an EC50 of 7 nM[1].

[1]. Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11(4):1074-81.

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