Poricoic acid A |
| Katalog-Nr.GC36948 |
Die aus Poria cocos isolierte PoricoinsÄure A besitzt eine AntitumoraktivitÄt. PoricoinsÄure A verstÄrkt die Melatonin-Hemmung des AKI-zu-CKD-Übergangs durch Regulierung der Gas6/AxlNFκB/Nrf2-Achse.
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Cas No.: 137551-38-3
Sample solution is provided at 25 µL, 10mM.
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Poricoic acid A, isolated from Poria cocos, possesses anti-tumor activity[1]. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis[2].
[1]. Dong H, et al. Enrichment and separation of antitumor triterpene acids from the epidermis of Poria cocos by pH-zone-refining counter-current chromatography and conventional high-speed counter-current chromatography. J Sep Sci. 2015 Jun;38(11):1977-82. [2]. Chen DQ, et al. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis. Free Radic Biol Med. 2019 Apr;134:484-497.
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