Sigma-1 receptor antagonist 3 |
| Katalog-Nr.GC38048 |
Sigma-1-Rezeptor-Antagonist 3 (Verbindung 135) ist ein potenter und selektiver Sigma-1 (σ1)-Rezeptor-Antagonist mit einem Ki von 1,14 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1639220-17-9
Sample solution is provided at 25 µL, 10mM.
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Sigma-1 receptor antagonist 3 (compound135) is a potent and selective Sigma-1 (σ1) receptor antagonist with a Ki of 1.14 nM. Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG) with an IC50 of 1.54 μM. Sigma-1 receptor antagonist 3 is for treating neuropathic pain[1].
[1]. Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57(24):10404-23.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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