Hyocholic Acid (Synonyms: γ-Muricholic Acid) |
| Katalog-Nr.GC40717 |
Hyocholsäure ist eine primäre Gallensäure bei Schweinen und anderen Säugetieren.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 547-75-1
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Hyocholic acid is a primary bile acid in pigs and other mammals. [1] It has also been found in urine samples from patients with cholestasis. [2] Hyocholic acid is converted by gut microflora primarily to taurohyocholate and, to a lesser extent, taurocholic acid and tauro-β-muricholic acid in mice.[3] Hyocholic acid has low toxicity against human hepatoma HepG2 cells.[3][4]
Reference
[1]. Lundell, K., and Wikvall, K. Species-specific and age-dependent bile acid composition: Aspects on CYP8B and CYP4A subfamilies in bile acid biosynthesis. Curr. Drug Metab. 9(4), 323-331 (2008).
[2]. van Berge Henegouwen, G.P., Brandt, K.H., Eyssen, H., et al. Sulphated and unsulphated bile acids in serum, bile, and urine of patients with cholestasis. Gut 17(11), 861-869 (1976).
[3]. Wang, D.Q.-H., Tazuma, S., Cohen, D.E., et al. Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: Studies in the gallstone-susceptible mouse. Am. J. Physiol Gastrointest. Liver Physiol. 285(3), G494-G502 (2003).
[4]. Perreault, M., Bialek, A., Trottier, J., et al. Role of glucuronidation for hepatic detoxification and urinary elimination of toxic bile acids during biliary obstruction. PLoS One 8(11), e80994 (2013).
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *