JAK-IN-3 |
| Katalog-Nr.GC65453 |
JAK-IN-3 (Verbindung 22) ist ein potenter JAK-Inhibitor mit IC50-Werten von 3 nM, 5 nM, 34 nM und 70 nM fÜr JAK3, JAK1, TYK2 bzw. JAK2.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1400876-94-9
Sample solution is provided at 25 µL, 10mM.
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JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively[1].
[1]. Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.
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