Kobophenol A |
| Katalog-Nr.GC64263 |
Kobophenol A, ein oligomeres Stilben, blockiert die Interaktion zwischen dem ACE2-Rezeptor und S1-RBD mit einem IC50 von 1,81 μM und hemmt die SARS-CoV-2-Virusinfektion in Zellen mit einem EC50 von 71,6 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 124027-58-3
Sample solution is provided at 25 µL, 10mM.
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Kobophenol A, an oligomeric stilbene, blocks the interaction between the ACE2 receptor and S1-RBD with an IC50 of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM. Kobophenol A inhibits the activity of partially purified rat brain protein kinase C (PKC) with an IC50 of 52 µM[1][2].
[1]. Gangadevi S, et al. Kobophenol A Inhibits Binding of Host ACE2 Receptor with Spike RBD Domain of SARS-CoV-2, a Lead Compound for Blocking COVID-19. J Phys Chem Lett. 2021;12(7):1793-1802.
[2]. Xu G, Zhang LP, Chen LF, Hu CQ. Yao Xue Xue Bao. 1994;29(11):818-822.
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