L-Selenocystine (Synonyms: Seleno-L-cystine) |
| Katalog-Nr.GC44084 |
L-Selenocystin ist eine Diselenid-verbrÜckte AminosÄure.
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Cas No.: 29621-88-3
Sample solution is provided at 25 µL, 10mM.
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L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 µM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.
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