PDK4-IN-1 hydrochloride |
| Katalog-Nr.GC39500 |
PDK4-IN-1-Hydrochlorid ist ein Anthrachinon-Derivat und ein potenter und oral aktiver Pyruvat-Dehydrogenase-Kinase-4 (PDK4)-Inhibitor mit einem IC50-Wert von 84 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2310262-11-2
Sample solution is provided at 25 µL, 10mM.
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PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 hydrochloride potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 hydrochloride has antidiabetic, anticancer and anti-allergic activity[1].
[1]. Lee D, et al. Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases. J Med Chem. 2019 Jan 24;62(2):575-588.
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
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