Pomalidomide 4'-PEG2-amine (Synonyms: Thalidomide-NH-PEG2-C2-NH2 hydrochloride) |
| Katalog-Nr.GC50530 |
Pomalidomide 4'-PEG2-Amin ist ein synthetisiertes E3-Ligase-Ligand-Linker-Konjugat, das den auf Thalidomid basierenden Cereblon-Liganden und den 2-Einheiten-PEG-Linker enthÄlt, die in der PROTAC-Technologie verwendet werden.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2245697-87-2
Sample solution is provided at 25 µL, 10mM.
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Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 1 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Remillard et al (2017) Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 56 5738 PMID:28418626
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
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