Adaptive Immunity

15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 formed by 15-hydroxy PGDH.

Dimethoxycurcumin ist ein Derivat von Curcumin, das entzÜndungshemmende und antioxidative Wirkungen hat.

C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM).

C6 L-threo Ceramide (d18:1/6:0) ist ein bioaktives Sphingolipid und zelldurchlÄssiges Analogon natÜrlich vorkommender Ceramide.

C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.

An S1P 1 receptor agonist

FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.

Isogarcinol is a polyprenylated benzophenone natural compound extracted from plants of the Garciniagenus. Isogarcinol is also an effective inhibitor of acetylcholinesterase (AChE; IC₅₀=1.13μM) and butyrylcholinesterase (BChE; IC₅₀=8.30μM).

1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.

Tyvelose is an unusual 3,6-dideoxyhexose terminal sugar and the immunodominant component of glycoprotein antigens in the parasitic helminth T.

MycophenolsÄure β-D-Glucuronid ist ein Metabolit des Immunsuppressivums MycophenolsÄure (MPA). MycophenolsÄure β-D-Glucuronid zeigt AntitumoraktivitÄt und kann in der Adenokarzinomforschung verwendet werden.

Matairesinol verleiht einem allergischen Dermatitis-Mausmodell antiallergische Wirkungen.

Trans-UrocansÄure (trans-UCA), ein natÜrlicher epidermaler Bestandteil, hemmt die AktivitÄt der menschlichen natÜrlichen Killerzellen (NK) in vitro.

Synthetic and natural alkyl phosphates, also known as phosphoantigens, stimulate the proliferation of γδ-T lymphocytes.

1-Palmitoyl-2-hydroxy-sn-glycero-3-PC ist ein hÄufig vorkommendes Gonaden-LPC (Lysophosphatidylcholin).

Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine.

3-Deaza-2'-deoxyadenosine strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM.

8-Bromoguanosine is a brominated derivative of guanosine.

9-Deazaguanine is a purine nucleoside analog with oral activity, functioning as a potent inhibitor of purine nucleoside phosphorylase (PNP).

ABC34 is an inactive control probe for JJH260, the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).

Ac-ANW-AMC ist ein fluorogenes Substrat fÜr Immunoproteasom.

Ac-IEPD-AMC is a fluorogenic substrate for granzyme B.

AUY954 is an orally bioavailable and selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1; EC50 = 1.2 nM for stimulating GTPγS binding to S1P1 in CHO cells).

Azido-FTY720 ist ein photoaktivierbares Analogon von FTY720.