Metabolism
Research Areas
- PPAR(229)
- Sterol Biosynthesis(40)
- 5-alpha Reductase(10)
- 5-Lipoxygenase(11)
- Aminopeptidase(13)
- Adenosine Deaminase(6)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(55)
- CETP(11)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(19)
- Dehydrogenase(36)
- DHFR(7)
- DGAT(7)
- Dopamine β-hydroxylase(10)
- Enolase(6)
- FAAH(36)
- Factor Xa(59)
- Ferroptosis(211)
- Folate Analogue(2)
- Glucokinase(17)
- HLE
- HMG-CoA Reductase(38)
- HSP(75)
- IDO(46)
- KRAS-PDEδ(3)
- MAO(6)
- Metabolic Enzymes(48)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(27)
- P450(156)
- PDE(257)
- Phospholipase(136)
- Procollagen C Proteinase(1)
- Saccharometabolism(1)
- SCD(19)
- SGLT(29)
- TPH(4)
- Transferase(21)
- Energy Metabolism
- Inorganic Ions
- ALP(1)
- Carbohydrates(33)
- Uric Acid
- Muscle Metabolism
- MDA
- MPO
- Transaminase(1)
- Glutathione Reductase(1)
- Thioredoxin Reductase
- Catalase(12)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(17)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(102)
- Pyruvate kinase(16)
- Others(4)
- MGL(1)
- Galactosidase(1)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(12)
- Dihydroorotate Dehydrogenase(15)
- Bile Acids & Microbiome(104)
- Bone Growth & Remodeling(53)
- Carbohydrate Metabolism(158)
- Cofactors & Vitamins(82)
- Dyslipidemias(104)
- Inborn Errors of Metabolism(96)
- Metabolic Syndrome(21)
- Necroptosis(18)
- Necrosis(16)
- Nutrient Sensing(14)
- Phosphodiesterase(34)
- Reproductive Biology(177)
- Thermogenesis(8)
- Prolyl Hydroxylation Enzymes(2)
- Biliary System(11)
- Fat Mass and Obesity-associated Protein (FTO)(6)
- SHIP(1)
- Liposome(53)
- MetAP
- PGC-1α(7)
- PI5P4K(2)
- FOXO(1)
- Furin(3)
- Metabolic Diseases(8)
- Neuronal Signaling(4)
Products Related to Metabolism(2997)
- GC79746N-Palmitoyl-l-leucineCAS: 14379-42-1Purity: >99.50%
N-Palmitoyl-l-leucine (GK144) is a secreted phospholipases A 2 inhibitor.
- GC79747BAPTA tetracesiumCAS: 480436-84-8Purity: >98%
BAPTA tetracesium is a selective and cell-impermeant chelator for calcium.
- GC79758PAI-1-IN-1CAS: 1247823-40-0Purity: >99.00%
PAI-1-IN-1 is an orally active and specific PAI-1 inhibitor with an IC 50 of <6.95 μM.
- GC79764(E/Z)-ABP/PPAR modulator 1Purity: >97.00%
(E/Z)-ABP/PPAR modulator 1 is a mixture of the E and Z isomers of ABP/PPAR modulator 1.
- GC79862Sulfaphenazole-d 4CAS: 2702538-04-1Purity: >99.50%
Sulfaphenazole -d 4 is the deuterium labeled Sulfaphenazole.
- GC79865Sildenafil-d 3 citratePurity: >98%
Sildenafil-d 3 citrate (UK-92480-d 3 citrate) is the deuterium labeled Sildenafil citrate.
- GC79872RhoNox-4CAS: 2711762-70-6Purity: >98.50%
RhoNox-4 is a ferroptosis inhibitor and a fluorescence activation indicator specific to Fe 2+. RhoNox-4 selectively reacts with labile Fe 2+ and oxidizes it to Fe 3+, depleting labile Fe 2+ involved in lipid peroxidation and inhibiting ferroptosis induced by ferroptosis inducers.
- GC79873LPd peroxida probe-2CAS: 3092823-52-1Purity: >99.00%
LPd peroxida probe-2 (Compound I-1) is a lipid peroxidation fluorescent indicator (Ex = 488 nm, Em = 535 nm).
- GC80469ω-Hexatoxin-Hv1a TFAPurity: >97.00%
ω-Hexatoxin-Hv1a (ω-ACTX-Hv1; ω-Atracotoxin-HV1) TFA is an orally active insecticidal neurotoxin containing an inhibitor cystine knot motif and a selective calcium channel inhibitor.
- GC80478Acetyl coenzyme A-d 3CAS: 121443-44-5Purity: >98.00%
Acetyl coenzyme A -d 3 (Acetyl-CoA-d 3 ) is the deuterium labeled Acetyl coenzyme A.
- GC80479DSPE-PEG2000-Carboxy NHS sodiumCAS: 2410279-87-5Purity: >98%
DSPE-PEG2000-Carboxy NHS sodium is a linker.
- GC80481CCT-010354CAS: 32549-31-8Purity: >99.00%
CCT-010354 (Compound 63e) is an agent intermediate that can be used to synthesize PPARα/δ dual agonist [1] .
- GC80485PF-06445974 precursorCAS: 2055777-51-8Purity: >99.50%
PF-06445974 precursor (Compound 28) is a nitro precursor and synthetic intermediate.
- GC80488(S)-NerandomilastCAS: 1423719-31-6Purity: >98.50%
(S)-Nerandomilast ((S)-BI 1015550) is the S-isomer of Nerandomilast.
- GC80489(rac)-NerandomilastCAS: 1423719-27-0Purity: >99.50%
(rac)-Nerandomilast ((rac)-BI 1015550) is a mixture of enantiomeric isomers of Nerandomilast, among which only the (R)-enantiomer (i.e., Nerandomilast ) has PDE4B inhibitory activity; the (S)-enantiomer (i.e., (S)-Nerandomilast ) is basically inactive.
- GC80871IsopsoralidinCAS: 3564-61-2Purity: >98.00%
Isopsoralidin is a phosphatidylinositol 3-kinase ( PI3K ) inhibitor with potential hepatotoxicity and CYP2D6 inhibitory activity [1] .
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC79744 | GRI918013 | 313685-55-1 | >98% | |
GRI918013 (compound 1) is a selective and competitive autotaxin (ATX/NPP2) inhibitor with anti-invasiv e and anti-metastatic activity. | ||||
| GC79745 | PDE4B modulator-1 | 848057-26-1 | >98.00% | |
PDE4B modulator-1 is a PDE4B modulator. | ||||
| GC79746 | N-Palmitoyl-l-leucine | 14379-42-1 | >99.50% | |
N-Palmitoyl-l-leucine (GK144) is a secreted phospholipases A 2 inhibitor. | ||||
| GC79747 | BAPTA tetracesium | 480436-84-8 | >98% | |
BAPTA tetracesium is a selective and cell-impermeant chelator for calcium. | ||||
| GC79758 | PAI-1-IN-1 | 1247823-40-0 | >99.00% | |
PAI-1-IN-1 is an orally active and specific PAI-1 inhibitor with an IC 50 of <6.95 μM. | ||||
| GC79762 | BGT-002 | 2127387-94-2 | >99.00% | |
BGT-002 (326E) is an orally active dual ACLY inhibitor and PPARα agonist. | ||||
| GC79764 | (E/Z)-ABP/PPAR modulator 1 | - | >97.00% | |
(E/Z)-ABP/PPAR modulator 1 is a mixture of the E and Z isomers of ABP/PPAR modulator 1. | ||||
| GC79839 | Aldoview | 1356479-94-1 | >99.00% | |
AldoView (Compound 3) is an intermediate. | ||||
| GC79862 | Sulfaphenazole-d 4 | 2702538-04-1 | >99.50% | |
Sulfaphenazole -d 4 is the deuterium labeled Sulfaphenazole. | ||||
| GC79865 | Sildenafil-d 3 citrate | - | >98% | |
Sildenafil-d 3 citrate (UK-92480-d 3 citrate) is the deuterium labeled Sildenafil citrate. | ||||
| GC79872 | RhoNox-4 | 2711762-70-6 | >98.50% | |
RhoNox-4 is a ferroptosis inhibitor and a fluorescence activation indicator specific to Fe 2+. RhoNox-4 selectively reacts with labile Fe 2+ and oxidizes it to Fe 3+, depleting labile Fe 2+ involved in lipid peroxidation and inhibiting ferroptosis induced by ferroptosis inducers. | ||||
| GC79873 | LPd peroxida probe-2 | 3092823-52-1 | >99.00% | |
LPd peroxida probe-2 (Compound I-1) is a lipid peroxidation fluorescent indicator (Ex = 488 nm, Em = 535 nm). | ||||
| GC80469 | ω-Hexatoxin-Hv1a TFA | - | >97.00% | |
ω-Hexatoxin-Hv1a (ω-ACTX-Hv1; ω-Atracotoxin-HV1) TFA is an orally active insecticidal neurotoxin containing an inhibitor cystine knot motif and a selective calcium channel inhibitor. | ||||
| GC80478 | Acetyl coenzyme A-d 3 | 121443-44-5 | >98.00% | |
Acetyl coenzyme A -d 3 (Acetyl-CoA-d 3 ) is the deuterium labeled Acetyl coenzyme A. | ||||
| GC80479 | DSPE-PEG2000-Carboxy NHS sodium | 2410279-87-5 | >98% | |
DSPE-PEG2000-Carboxy NHS sodium is a linker. | ||||
| GC80481 | CCT-010354 | 32549-31-8 | >99.00% | |
CCT-010354 (Compound 63e) is an agent intermediate that can be used to synthesize PPARα/δ dual agonist [1] . | ||||
| GC80485 | PF-06445974 precursor | 2055777-51-8 | >99.50% | |
PF-06445974 precursor (Compound 28) is a nitro precursor and synthetic intermediate. | ||||
| GC80488 | (S)-Nerandomilast | 1423719-31-6 | >98.50% | |
(S)-Nerandomilast ((S)-BI 1015550) is the S-isomer of Nerandomilast. | ||||
| GC80489 | (rac)-Nerandomilast | 1423719-27-0 | >99.50% | |
(rac)-Nerandomilast ((rac)-BI 1015550) is a mixture of enantiomeric isomers of Nerandomilast, among which only the (R)-enantiomer (i.e., Nerandomilast ) has PDE4B inhibitory activity; the (S)-enantiomer (i.e., (S)-Nerandomilast ) is basically inactive. | ||||
| GC80490 | (Rac)-LRK-4189 | 3063345-48-9 | >96.50% | |
(Rac)-LRK-4189 is the racemate of LRK-4189. | ||||
| GC80865 | Anandamide- 15 N | - | >99.50% | |
Anandamide - 15 N (AEA- 15 N) is the 15 N-labeled Anandamide. | ||||
| GC80871 | Isopsoralidin | 3564-61-2 | >98.00% | |
Isopsoralidin is a phosphatidylinositol 3-kinase ( PI3K ) inhibitor with potential hepatotoxicity and CYP2D6 inhibitory activity [1] . | ||||
| GC81023 | 5-Iodo-BIIB021 | 911397-54-1 | >98.00% | |
5-Iodo-BIIB021 is a HSP90 ligand. | ||||
| GC81025 | PSP-0119 | 3104855-98-0 | >98.50% | |
PSP-0119 is a highly efficient and effective PROTAC degrader targeting IRAK4 ( IC 50 = 2.83 nM). | ||||