Metabolism
Research Areas
- PPAR(229)
- Sterol Biosynthesis(40)
- 5-alpha Reductase(10)
- 5-Lipoxygenase(11)
- Aminopeptidase(13)
- Adenosine Deaminase(6)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(55)
- CETP(11)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(19)
- Dehydrogenase(36)
- DHFR(7)
- DGAT(7)
- Dopamine β-hydroxylase(10)
- Enolase(6)
- FAAH(36)
- Factor Xa(59)
- Ferroptosis(211)
- Folate Analogue(2)
- Glucokinase(17)
- HLE
- HMG-CoA Reductase(38)
- HSP(75)
- IDO(46)
- KRAS-PDEδ(3)
- MAO(6)
- Metabolic Enzymes(48)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(27)
- P450(156)
- PDE(257)
- Phospholipase(136)
- Procollagen C Proteinase(1)
- Saccharometabolism(1)
- SCD(19)
- SGLT(29)
- TPH(4)
- Transferase(21)
- Energy Metabolism
- Inorganic Ions
- ALP(1)
- Carbohydrates(33)
- Uric Acid
- Muscle Metabolism
- MDA
- MPO
- Transaminase(1)
- Glutathione Reductase(1)
- Thioredoxin Reductase
- Catalase(12)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(17)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(102)
- Pyruvate kinase(16)
- Others(4)
- MGL(1)
- Galactosidase(1)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(12)
- Dihydroorotate Dehydrogenase(15)
- Bile Acids & Microbiome(104)
- Bone Growth & Remodeling(53)
- Carbohydrate Metabolism(158)
- Cofactors & Vitamins(82)
- Dyslipidemias(104)
- Inborn Errors of Metabolism(96)
- Metabolic Syndrome(21)
- Necroptosis(18)
- Necrosis(16)
- Nutrient Sensing(14)
- Phosphodiesterase(34)
- Reproductive Biology(177)
- Thermogenesis(8)
- Prolyl Hydroxylation Enzymes(2)
- Biliary System(11)
- Fat Mass and Obesity-associated Protein (FTO)(6)
- SHIP(1)
- Liposome(53)
- MetAP
- PGC-1α(7)
- PI5P4K(2)
- FOXO(1)
- Furin(3)
- Metabolic Diseases(8)
- Neuronal Signaling(4)
Products Related to Metabolism(2997)
- GC81323PDGFRA/CAIX/XII-IN-1Purity: >98.00%
PDGFRA/CAIX/XII-IN-1 is an inhibitor of PDGFRA, CA IX and CA XII, with an IC 50 of 20 nM against PDGFRA, a K i of 93.3 nM against CA IX, and a K i of 80.0 nM against CA XII.
- GC81421ZY-2 (solution)Purity: >98%
ZY-2 (solution) is a fluorescent probe targeting pyruvate kinase M2 ( PKM2 ) with an excitation wavelength of 419 nm.
- GC81431(S,S,S)-Icafolin-methylCAS: 2254813-53-9Purity: >99.50%
(S,S,S)-Icafolin-methyl is an isomer of Icafolin-methyl.
- GC81445S-Adenosyl-3-thiopropylamineCAS: 53186-57-5Purity: >98.00%
S-Adenosyl-3-thiopropylamine acts as a weak to moderate reversible inhibitor of spermidine/spermine synthase, and its inhibitory activity increases after oxidation (to S-Adenosyl-3-thiopropylamine sulphoxide and S-Adenosyl-3-thiopropylamine sulphone) [1] .
- GC81449FlupropanateCAS: 756-09-2Purity: >99.50%
Flupropanate (2,2,3,3-Tetrafluoropropionic acid; 3H-Tetrafluoropropionic acid) is a soil-active selective herbicide and plant growth inhibitor that acts by inhibiting radicle growth and lipid biosynthesis in sensitive plants.
- GC81450Iodosulfuron-methyl sodiumCAS: 144550-36-7Purity: >98%
Iodosulfuron-methyl sodium is a sulfonylurea herbicide.
- GC81451TolpyralateCAS: 1101132-67-5Purity: >98%
Tolpyralate is a selective post-emergence herbicide and corn Herbicide.
- GC81454D-Val-Gly-Arg-pNA acetatePurity: >99.50%
D-Val-Gly-Arg-pNA acetate is a chromogenic substrate of TPA (tissue plasminogen activator).
- GC81455CMP-SiaNAz sodiumPurity: >93.00%
CMP-SiaNAz (CMP-NeuNAz) sodium is a sialic acid nucleotide sugar derivative.
- GC81538RSL3-NH2 hydrochlorideCAS: 3051815-40-5Purity: >98.00%
RSL3-NH2 hydrochloride is a GPX4 inhibitor and ferroptosis inducer.
- GC81543GPX4-IN-19CAS: 3102894-57-2Purity: >99.00%
GPX4-IN-19 is an effective GPX4 inhibitor ( IC 50 = 0.311 μM), covalently binds to the Sec 46 site of GPX4.
- GC81545Ferroptosis inducer-12Purity: >96.00%
Ferroptosis inducer-12 is a potent and selective ferroptosis inducer.
- GC815713,4,6-Tri-O-galloyl-D-glucoseCAS: 99523-99-6Purity: >98%
3,4,6-Tri-O-galloyl-D-glucose (3,4,6-Trigalloylglucose) is an α-amylase ( porcine α-amylase IC 50 = 334.6 μM; K i = 307.5 μM) and α-glucosidase ( yeast α-glucosidase IC 50 = 46.5 μM; K i = 39.9 μM) mixed type inhibitor.
- GC81575ZIP14-IN-1CAS: 1048-17-5Purity: >99.50%
ZIP 14-IN-1 (PPTD) is a selective and orally active ZIP14 inhibitor.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81323 | PDGFRA/CAIX/XII-IN-1 | - | >98.00% | |
PDGFRA/CAIX/XII-IN-1 is an inhibitor of PDGFRA, CA IX and CA XII, with an IC 50 of 20 nM against PDGFRA, a K i of 93.3 nM against CA IX, and a K i of 80.0 nM against CA XII. | ||||
| GC81421 | ZY-2 (solution) | - | >98% | |
ZY-2 (solution) is a fluorescent probe targeting pyruvate kinase M2 ( PKM2 ) with an excitation wavelength of 419 nm. | ||||
| GC81429 | Mansonone E | 81845-40-1 | >99.00% | |
Mansonone E (Compound 5) is a pesticide. | ||||
| GC81430 | 3-Hydroxyindole | 480-93-3 | >87.50% | |
3-Hydroxyindole is a hydroxyindole compound. | ||||
| GC81431 | (S,S,S)-Icafolin-methyl | 2254813-53-9 | >99.50% | |
(S,S,S)-Icafolin-methyl is an isomer of Icafolin-methyl. | ||||
| GC81439 | SZ0232 | 924851-91-2 | >99.00% | |
SZ0232 is a selective mPGES-2 inhibitor. | ||||
| GC81445 | S-Adenosyl-3-thiopropylamine | 53186-57-5 | >98.00% | |
S-Adenosyl-3-thiopropylamine acts as a weak to moderate reversible inhibitor of spermidine/spermine synthase, and its inhibitory activity increases after oxidation (to S-Adenosyl-3-thiopropylamine sulphoxide and S-Adenosyl-3-thiopropylamine sulphone) [1] . | ||||
| GC81448 | Indaziflam | 950782-86-2 | >99.50% | |
Indaziflam is an alkyltriazine herbicide. | ||||
| GC81449 | Flupropanate | 756-09-2 | >99.50% | |
Flupropanate (2,2,3,3-Tetrafluoropropionic acid; 3H-Tetrafluoropropionic acid) is a soil-active selective herbicide and plant growth inhibitor that acts by inhibiting radicle growth and lipid biosynthesis in sensitive plants. | ||||
| GC81450 | Iodosulfuron-methyl sodium | 144550-36-7 | >98% | |
Iodosulfuron-methyl sodium is a sulfonylurea herbicide. | ||||
| GC81451 | Tolpyralate | 1101132-67-5 | >98% | |
Tolpyralate is a selective post-emergence herbicide and corn Herbicide. | ||||
| GC81452 | IP6K-IN-2 | 3024590-83-5 | >99.50% | |
IP6K-IN-2 is an inositol hexakisphosphate kinase (IP6K1) inhibitor that inhibits IP6K1 enzyme activity with an IC 50 value of 110 nM. | ||||
| GC81454 | D-Val-Gly-Arg-pNA acetate | - | >99.50% | |
D-Val-Gly-Arg-pNA acetate is a chromogenic substrate of TPA (tissue plasminogen activator). | ||||
| GC81455 | CMP-SiaNAz sodium | - | >93.00% | |
CMP-SiaNAz (CMP-NeuNAz) sodium is a sialic acid nucleotide sugar derivative. | ||||
| GC81457 | (S)-Isobutyl lactate | 63697-00-7 | >98.00% | |
(S)-Isobutyl lactate is an intermediate. | ||||
| GC81499 | CT-179 | 1996636-69-1 | >99.50% | |
CT-179 is a brain-penetrant and orally active OLIG2 inhibitor with a human IC 50 of 1250 nM. | ||||
| GC81519 | SHP1-IN-2 | - | >97.00% | |
SHP1‑IN‑2 is a selective and orally active SHP1 inhibitor. | ||||
| GC81538 | RSL3-NH2 hydrochloride | 3051815-40-5 | >98.00% | |
RSL3-NH2 hydrochloride is a GPX4 inhibitor and ferroptosis inducer. | ||||
| GC81543 | GPX4-IN-19 | 3102894-57-2 | >99.00% | |
GPX4-IN-19 is an effective GPX4 inhibitor ( IC 50 = 0.311 μM), covalently binds to the Sec 46 site of GPX4. | ||||
| GC81545 | Ferroptosis inducer-12 | - | >96.00% | |
Ferroptosis inducer-12 is a potent and selective ferroptosis inducer. | ||||
| GC81546 | iMQT_020 | 2463893-46-9 | >99.00% | |
iMQT_020 is a selective allosteric SLC1A5_var inhibitor. | ||||
| GC81571 | 3,4,6-Tri-O-galloyl-D-glucose | 99523-99-6 | >98% | |
3,4,6-Tri-O-galloyl-D-glucose (3,4,6-Trigalloylglucose) is an α-amylase ( porcine α-amylase IC 50 = 334.6 μM; K i = 307.5 μM) and α-glucosidase ( yeast α-glucosidase IC 50 = 46.5 μM; K i = 39.9 μM) mixed type inhibitor. | ||||
| GC81575 | ZIP14-IN-1 | 1048-17-5 | >99.50% | |
ZIP 14-IN-1 (PPTD) is a selective and orally active ZIP14 inhibitor. | ||||
| GC81590 | Onjisaponin R | 1008798-85-3 | >98% | |
Onjisaponin R is an α-amylase inhibitor. | ||||
