RU 24969 hemisuccinate |
| Katalog-Nr.GC50006 |
RU 24969-Hemisuccinat ist ein bevorzugter 5-HT1B-Agonist mit einem Ki von 0,38 nM, zeigt aber auch eine betrÄchtliche AffinitÄt fÜr den 5-HT1A-Rezeptor (Ki = 2,5 nM) und hat eine geringe AffinitÄt fÜr andere Rezeptorstellen im Gehirn.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 66611-27-6
Sample solution is provided at 25 µL, 10mM.
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Potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.
Gudermann et al (1993) Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Mol.Pharmacol. 43 412 PMID:8450834 |Tomkins and O'Neill (2000) Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 66 129 PMID:10837852 |Guillaume et al (1987) Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antiDArgic properties. Eur.J.Med.Chem. 22 33
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