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TCMDC-135051

Katalog-Nr.GC39162

TCMDC-135051 ist ein hochselektiver und potenter Proteinkinase-PfCLK3-Inhibitor mit geringer Off-Target-ToxizitÄt.

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TCMDC-135051 Chemische Struktur

Cas No.: 2413716-15-9

Größe Preis Lagerbestand Menge
5mg
324,00 $
Auf Lager
10mM/1ml
510,00 $
Auf Lager
50mg
1.530,00 $
Auf Lager
100mg
2.086,00 $
Auf Lager
200mg Please Inquire Please Inquire
500mg Please Inquire Please Inquire

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

TCMDC-135051 is a highly selective and potent protein kinase PfCLK3 inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 has antiparasiticidal activity (EC50=320 nM)[1].

[1]. Alam MM, et al. Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science. 2019 Aug 30;365(6456). pii: eaau1682.

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Average Rating: 5 ★★★★★ (Based on Reviews and 22 reference(s) in Google Scholar.)

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