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Thrombin inhibitor 1

Katalog-Nr.GC32639

Thrombin-Inhibitor 1 ist ein potenter Thrombin-Inhibitor (Ki = 0,66 nM, 2xaPTT = 0,43 μM).

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Thrombin inhibitor 1 Chemische Struktur

Cas No.: 855998-46-8

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM).

Thrombin inhibitor 1 (Compound 4) is binds in the active site of thrombin with Ki of 0.66 nM, 2xaPTT=0.43 uM). Thrombin inhibitor 1 (Compound 4) is evaluated for its thrombin inhibitory potency and its functional ability to double the activated partial thromboplastin time (2xaPTT) in human plasma with a 2xaPTT of 0.43 μM[1].

[1]. Nantermet PG, et al. P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2771-5.

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