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trans-Ned 19

Katalog-Nr.GC16322

trans-Ned 19, ein NAADP-Antagonist und TPC-Blocker, unterdrÜckt das Calciumsignal in humanen Nabelvenen-Endothelzellen (HUVEC) und die Relaxation der Rattenaorta als Reaktion auf niedrige Histaminkonzentrationen.

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trans-Ned 19 Chemische Struktur

Cas No.: 1354235-96-3

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

trans-Ned 19, a NAADP antagonist and TPC blocker, suppresses the calcium signal in human umbilical vein endothelial cells (HUVEC) and the rat aorta relaxation in response to low histamine concentrations[1].

References:
[1]. Zharkich IL, et al. Suppression of Histamine-Induced Relaxation of Rat Aorta and Calcium Signaling in Endothelial Cells by Two-Pore Channel Blocker trans-NED19 and Hydrogen Peroxide. Izv Akad Nauk Ser Biol. 2016 Jul;(4):430-438.

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