A ubiquitous metabolite that participates in numerous physiological processes, including transsulfuration, polyamine biosynthesis, and transmethylation is the ademetionine also known as S-adenosyl-L-methionine (AdoMet), SAM or SAMe ( Glpbio ).

A macrolide antibiotic, tylosin is active against gram-positive aerobic bacteria and mycoplasmas throughout a wide range of conditions. It is authorized for the treatment of a number of infectious disorders in cattle and poultry, including mastitis, respiratory conditions, and farm animal dysentery.

Dans les numéros précédents, nous avons présentédiverses formulations et stratégies pour la dissolution des médicaments. Parmi elles, le DMSO, qui n'est pas recommandé, a également sa place en tant que co-solvant, mais il est assez controversé.L'utilisation de ce solvant, restreinte par la FDA, est largement répandue et est hautement toxique.Quelle est son toxicité et comment l'utilisons-nous dans nos expériences ? Aujourd'hui, nous allonsvous révéler la bonne utilisation du "solvant universel" DMSO dans les expériences cellulaires et animales.

Brent R. Stockwell, l’auteur de l’origine de la ferroptose, a rédigé une revue sur les progrès de la recherche pour le 10e anniversaire de la ferroptose, publiée dans le journal Cell avec un facteur d'impact élevé de 66,85 .

Introduction: RSM-932A, also known as TCD- 717, is a ChoKα asset, which targets the mortal choline kinase nascence, an enzyme involved in increased lipid metabolism of cancer cells. RSM-932A appears to have an altogether new medium of inhibition and is synergistic with respect to both choline and ATP. RSM-932A have in vitro inhibitory exertion in the low nanomolar range.

The sodium salt of palmitic acid, sodium palmitate ( Hexadecanoic acid sodium salt, Palmitic acid sodium salt) , produced during the process of fatty acid synthesis present in fats and waxes. It is produced synthetically and driven by palm oil. Plays major role as an emulsifier.

Brent R. Stockwell, the author of the origin of Ferroptosis, has written a review about research progress for the 10th anniversary of Ferroptosis, published in the journal Cell with a high impact factor of 66.85 (2022). The National Nature Foundation projects and the amount of money winning the bid in this direction are rising year by year, and the relevant research papers are also repeatedly topping the CNS! (Figure 1)

Il existe diverses voies d'administration dans les études expérimentales animales, telles que l'administration orale, intrapéritonéale, intraveineuse, intracérébrale, etc. Cependant, nous choisissons souvent une méthode d'administration de médicaments couramment utilisée en laboratoire sans en connaître réellement la raison.

Alisol B (ALB), a triterpenoid compound extracted from Alisma, has been reported to ameliorate nonalcoholic steatohepatitis (NASH) and slow obesity.

Semaglutide is a polypeptide composed of 31 amino acids related by peptide bonds, with a molecular heaviness of 4114 g/mol. It actions as an agonist for glucagon-like peptide-1 receptors (GLP-1 R) and is functioned in the action of type 2 diabetes. Semaglutide purposes as a hypoglycemic agent, a GLP-1 receptor agonist, an anti-obesity mediator, a neuroprotective mediator, and want for food suppressant.