(±)-SDZ-201 106 (Synonyms: DPI 201-106) |
| カタログ番号GC41677 |
(±)-SDZ-201 106 (SDZ 201106) は、相乗的な筋細胞膜と細胞内の作用機序を持つ強心剤です。
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Cas No.: 97730-95-5
Sample solution is provided at 25 µL, 10mM.
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(±)-SDZ-201 106 is a diphenylpiperazinylindole derivative that prolongs the open state of cardiac voltage-gated Na+ channels. It has been shown to increase net Na+ influx and the activity of reverse mode Na+/Ca2+ exchange, which leads to an increase in intracellular Ca2+, as well as to partially inhibit the Na+ pump in cardiac myocytes. (±)-SDZ-201 106 is also reported to act as an open-channel blocker of delayed-rectifier K+ channels in NG108-15 neuronal cells.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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