Home>>Signaling Pathways>> Membrane Transporter/Ion Channel>>(±)-SDZ-201 106

(±)-SDZ-201 106 (Synonyms: DPI 201-106)

Catalog No.GC41677

(±)-SDZ-201 106 (SDZ 201106) is a cardiotonic agent with a synergistic sarcolemmal and intracellular mechanism of action.

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(±)-SDZ-201 106 Chemical Structure

Cas No.: 97730-95-5

Size Price Stock Qty
10mg
$43.00
In stock
25mg
$76.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

(±)-SDZ-201 106 is a diphenylpiperazinylindole derivative that prolongs the open state of cardiac voltage-gated Na+ channels. It has been shown to increase net Na+ influx and the activity of reverse mode Na+/Ca2+ exchange, which leads to an increase in intracellular Ca2+, as well as to partially inhibit the Na+ pump in cardiac myocytes. (±)-SDZ-201 106 is also reported to act as an open-channel blocker of delayed-rectifier K+ channels in NG108-15 neuronal cells.

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