5(S)-HETE lactone (Synonyms: 5(S)-Hydroxyeicosatetraenoic Acid lactone) |
| カタログ番号GC40829 |
5(S)-HETEラクトンは、5（S）-HETEのC-5ヒドロキシル基がC-1カルボキシル基に酸触媒下で求核付加反応を起こして形成された環状エステルです。
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Cas No.: 127708-42-3
Sample solution is provided at 25 µL, 10mM.
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5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE. The ability of (±)5-HETE lactone to inhibit rat basophilic leukemia cell 5-lipoxygenase (IC50 = 27 µM) may be entirely due to the 5(S) isomer, but the enantiomers have not been tested separately.
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