Antileukinate |
| カタログ番号GC42817 |
ヘキサペプチドであるアンチロイキネートは、CXC-ケモカイン受容体 (CXCR) の強力な阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 138559-60-1
Sample solution is provided at 25 µL, 10mM.
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Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 µM), prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. At 53 mg/kg, antileukinate has been shown to protect mice against acute pancreatitis and associated lung injury.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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